Optimized Self-Adaptive Power Distribution for Microgrids in a Typical Tourism Water Village of Northern China under COVID-19 Background

This work presents an improved self-adaptive power distribution approach for the microgrid in five modes under different pandemic conditions in a typical tourism water village in Northern China. Differently from the other studies, this work concentrates on satisfying the specific power supply requirements under the COVID-19 background, with the maximum value of the composite index as the object function. Composite index includes not only the economic factors, but also some compulsive factors to ensure the requested power supply of the residents/tourists. The improved particle swarm optimization method which employs the modified weighted factor and the elite strategy is utilized to optimize the power dispatching of the microgrid. Moreover, the impact of the pandemic has been fully considered by comparing the power dispatching before and after the pandemic. The case study in Baiyangdian Region confirms the effectiveness of the proposed method. With this method, the optimal power dispatching is determined under different modes.

C1q Complement/Tumor Necrosis Factor-Associated Proteins in Cardiovascular Disease and COVID-19.

With continually improving treatment strategies and patient care, the overall mortality of cardiovascular disease (CVD) has been significantly reduced. However, this success is a double-edged sword, as many patients who survive cardiovascular complications will progress towards a chronic disorder over time. A family of adiponectin paralogs designated as C1q complement/tumor necrosis factor (TNF)-associated proteins (CTRPs) has been found to play a role in the development of CVD. CTRPs, which are comprised of 15 members, CTRP1 to CTRP15, are secreted from different organs/tissues and exhibit diverse functions, have attracted increasing attention because of their roles in maintaining inner homeostasis by regulating metabolism, inflammation, and immune surveillance. In particular, studies indicate that CTRPs participate in the progression of CVD, influencing its prognosis. This review aims to improve understanding of the role of CTRPs in the cardiovascular system by analyzing current knowledge. In particular, we examine the association of CTRPs with endothelial cell dysfunction, inflammation, and diabetes, which are the basis for development of CVD. Additionally, the recently emerged novel coronavirus (COVID-19), officially known as severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has been found to trigger severe cardiovascular injury in some patients, and evidence indicates that the mortality of COVID-19 is much higher in patients with CVD than without CVD. Understanding the relationship of CTRPs and the SARS-CoV-2-related damage to the cardiovascular system, as well as the potential mechanisms, will achieve a profound insight into a therapeutic strategy to effectively control CVD and reduce the mortality rate.